井上 明宏
INOUE Akihiro
| 職名 | 教授 |
|---|---|
| 専門分野 | 細胞生物学、解剖生理学 |
| 連絡先 |
E-mail：a-inoue@redcross.ac.jp |
プロフィール
| 学歴 | 筑波大学大学院 医科学研究科 修士課程（医科学専攻） 修了 総合研究大学院大学 生命科学研究科 博士課程（生理科学専攻） 修了 |
|---|---|
| 学位 | 医科学修士（筑波大学） 博士（学術）（総合研究大学院大学） |
| 主要職歴 | 東京医科歯科大学大学院 医歯学総合研究科 准教授 |
| 担当授業科目 | 【学部】 「人体の構造と機能 I」 「人体の構造と機能 II」 「疾病の成り立ちと回復の促進 I」 「疾病の成り立ちと回復の促進 II」 「疾病の成り立ちと回復の促進 III」 「疾病の成り立ちと回復の促進 IV」 「基礎ゼミ I」 「基礎ゼミ II」 「研究 I」 「研究 II」 【大学院】 「病態生理学」（修士） 「人間総合講座」（修士） |
| 研究テーマ | 神経系の発生および神経細胞の形態と機能の研究 光活性化タンパク質を用いた細胞機能の研究 |
| 主要所属学会 | 日本解剖学会 日本神経科学学会 日本ヘルスコミュニケーション学会 |
主要著書・論文
1. Numano, F., Inoue, A., Enomoto, M., Shinomiya, K., Okawa, A. and Okabe, S. (2009). Critical involvement of Rho GTPase activity in the efficient transplantation of neural stem cells into the injured spinal cord. Molecular Brain, 2:37.
2. Yamagata, Y., Kobayashi, S., Umeda, T., Inoue, A., Sakagami, H., Fukaya, M., Watanabe, M., Hatanaka, N., Totsuka, M., Yagi, T., Obata, K., Imoto, K., Yanagawa, Y., Manabe, T. and Okabe, S. (2009). Kinase-dead knock-in mouse reveals an essential role of kinase activity of Ca2+/calmodulin-dependent protein kinase IIalpha in dendritic spine enlargement, long-term potentiation, and learning. Journal of Neuroscience, 29:7607-18.
3. Kuriu, T., Inoue, A., Bito, H., Sobue, K. and Okabe, S. (2006). Differential Control of Postsynaptic Density Scaffolds via Actin-Dependent and -Independent Mechanisms. Journal of Neuroscience, 26:7693-7706.
4. Iki, J., Inoue, A., Bito, H. and Okabe, S. (2005). Bi-directional regulation of postsynaptic cortactin distribution by BDNF and NMDA receptor activity. European Journal of Neuroscience, 22:2985-2994.
5. Nakazawa, T., Watabe, A.M., Tezuka, T., Yoshida, Y., Yokoyama, K., Umemori, H., Inoue, A., Okabe, S., Manabe, T. and Yamamoto, T. (2003). Molecular Biology of the Cell, 14:2921-2934.
6. Inoue, A. and Okabe, S. (2003). The dynamic organization of postsynaptic proteins: translocating molecules regulate synaptic function. Current. Opinion in Neurobiology, 13:332-340.
7. Inoue, A. and Sanes, J.R. (1997). Lamina-specific connectivity in the brain: roles for N-cadherin, neurotrophins and glycoconjugates. Science, 276: 1428-143.
8. Inoue, A., Takahashi, M., Hatta, K., Hotta, Y., and Okamoto, H. (1994). Developmental regulation of Isl-1 mRNA expression during neuronal differentiation in embryonic zebrafish. Developmental Dynamics, 199:1-11.
9. Kuwayama, H., Suzuki, M., Inoue, A., Kobayashi, H., Tanaka, H., Mikawa, T., Sugiura, M. and Ebashi, S. (1993). Amino acid sequence of myosin light chain kinase from bovine stomach with special references to its actin binding. Biomedical Research, 14:Suppl. 2, 113-116.
10. Inoue, A. and Akagawa, K. (1993). Neuron specific expression of a newly-identified cell membrane protein, HPC-1: Tissue distribution, and cellular and subcellular localization of immunoreactivity and mRNA. Molecular Brain Research, 19:121-128.
11. Kobayashi, H., Inoue, A., Mikawa, T., Kuwayama, H., Hotta, Y., Masaki, T., and Ebashi, S. (1992). Isolation of cDNA for bovine stomach 155kDa protein exhibiting myosin light chain kinase activity. Journal of. Biochemistry, 112:786-791.
12. Inoue, A. and Akagawa, K. (1992). Neuron-specific antigen HPC-1 from bovine brain reveals strong homology to epimorphin, an essential factor involved in epithelial morphogenesis: identification of a novel protein family. Biochemical and Biophysical Research Communications, 187:1144-1150.
13. Inoue, A., Obata, K. and Akagawa, K. (1992). Cloning and sequence analysis of cDNA for a neuronal cell membrane antigen, HPC-1. Journal of Biological Chemistry, 267:10613-10619.
14. Inoue, A., Yanagisawa, M. and Masaki, T. (1992). Differential tissue expression of multiple genes for smooth muscle/nonmuscle myosin light chains. Biochimica Biophysoica Acta, 1130:197-202.
15. Arinami, T., Ishikawa, M., Inoue, A., Yanagisawa, M., Masaki, T,. Yoshida, M.C. and Hamaguchi, H. (1991). American Journal of Human Genetics, 48, 990-996.
16. Masaki, T., Yanagisawa, M., Inoue, A., Kimura, S., and Goto, K. (1990). Study on the endothelin gene and its expression. Japanese Circulation Journal, 54, 1221-1225.
17. Inoue, A., Yanagisawa, M., Takano-Ohmuro, H. and Masaki, T. (1989). Two isoforms of smooth muscle myosin regulatory light chain in chicken gizzard. European Journal of. Biochemistry, 183:645-661.
18. Inoue, A., Yanagisawa, M. and Masaki, T. (1989). The human preproendothelin-1 gene: Complete nucleotide sequence and regulation of expression. Journal of Biological Chemistry, 264:25, 14954-14959.
19. Inoue, A., Yanagisawa, M., Kimura, S., Kasuya, Y., Miyauchi, T., Goto, K., and Masaki, T. (1989). The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proceedings of National Academy of. Sciences of the USA. 86, 2863-2867.
20. Yanagisawa, M., Inoue, A., Ishikawa, T., Kasuya, Y., Kimura, S., Kumagaye, S., Nakajima, K., Watanabe, T.X., Sakakibara, S., Goto, K. and Masaki, T. (1988). Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide. Proceedings of National Academy of Sciences of the USA, 85, 6964-6967.
21. Ito, Y., Yanagisawa, M., Ohkubo, M., Kimura, C., Kosaka, T., Inoue, A., Ishida, N., Mitsui, Y., Onda, H., Fujino, M. and Masaki, T. (1988). Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium-derived vasoconstrictor peptide, endothelin: Identity of human and porcine endothelin. FEBS Letters, 231, 2, 440-444.
